This is a next-generation small-molecule, peptide-like agonist targeting the ERR
(Estrogen-Related Receptor) family. In preclinical studies, it boosts mitochondrial function,
enhances endurance, and supports a leaner, more oxidative muscle profile.
Key Features
• Enhances mitochondrial energy output and increases oxidative metabolism.
• Improves endurance — ~70% greater running distance and ~45% longer duration in
preclinical models.
• Supports lean body composition with reduced fat mass and increased oxidative muscle
fibers.
• Exercise-mimetic activity: activates aerobic-exercise gene programs and mitochondrial
pathways.
• Metabolic benefits: improves glucose tolerance and insulin sensitivity in metabolicsyndrome
models.
• Pan-ERR activation: ERRα, ERRβ, and ERRγ agonist (EC₅₀ ≈ 98 / 230 / 430 nM),
influencing energy regulation in muscle, heart, and liver.
**Certificate of Analysis: Available upon request.